TRAF3

TRAF3
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1FLK, 1FLL, 1KZZ, 1L0A, 1RF3, 1ZMS, 2ECY, 2GKW
Dynodwyr
Cyfenwau	TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, TNF receptor associated factor 3, RNF118
Dynodwyr allanol	OMIM: 601896 HomoloGene: 7981 GeneCards: TRAF3
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• zinc ion binding; • signal transducer activity; • metal ion binding; • GO:0001948, GO:0016582 protein binding; • thioesterase binding; • protein phosphatase binding; • protein kinase binding; • ubiquitin protein ligase binding; • transferase activity; • GO:0050372 ubiquitin-protein transferase activity; • tumor necrosis factor receptor binding;
Cydrannau o'r gell	• cytoplasm; • cytosol; • endosome; • mitocondria; • cytoplasmic side of plasma membrane; • CD40 receptor complex; • GO:0009327 protein-containing complex;
Prosesau biolegol	• regulation of apoptotic process; • Toll signaling pathway; • immune system process; • TRIF-dependent toll-like receptor signaling pathway; • protein ubiquitination; • negative regulation of NF-kappaB transcription factor activity; • regulation of proteolysis; • GO:0097285 apoptotic process; • toll-like receptor signaling pathway; • GO:0032657 regulation of cytokine production; • GO:0072468 signal transduction; • regulation of interferon-beta production; • innate immune response; • tumor necrosis factor-mediated signaling pathway; • regulation of defense response to virus; • protein deubiquitination;
	Sources:Amigo / QuickGO
Orthologau
	7187
	n/a
	ENSG00000131323
	n/a
	Q13114
	n/a
NM_001199427; NM_003300; NM_145725; NM_145726; NM_001385142;
	NM_001385143
	n/a
	NP_001186356; NP_003291; NP_663777; NP_663778
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TRAF3 yw TRAF3 a elwir hefyd yn TNF receptor associated factor 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q32.32.^[2]

[1] "Human PubMed Reference:".

[2] TRAF3 - Cronfa NCBI

[1]

[2]